SC-GroupHK

Publications

You can also find my articles on my Google Scholar profile.

Book Chapters

2. Light Chains of the Botulinum Neurotoxins

  • Chen, S., Barbieri, J.T.
  • Neurotoxin. Edited by Keith Foster, Springer, CO, UK, 2013.

1. Clostridial Neurotoxins as Therapeutics

  • Chen, S.
  • Microbial Toxins — Genetics, Molecular Biology and Novel Applications. Edited by Thomas Proft, The Horizon Scientific Press, UK, 2013.

Patents

18. DRUG COMPOSITION, METHOD FOR TREATING INFECTION, DISINFECTING COMPOSITION, AND DRUG ADJUVANT

  • Non-Provisional Patent Application: PWG/PA/1135/12/2021 (US)

17. METHODS FOR TREATING BACTERIAL CELL POPULATIONS

  • PCT/CN2021/099665 — Filed Jun 11, 2021

16. 新型抗生素及其使用方法

  • 201880090658.2 / PCT/CN2018/122374 — Filed Dec 20, 2018 / Jan 3, 2018

15. 一种治疗耐碳青霉烯肺炎克雷伯氏菌感染的组合物

  • CB/P24320CNOO, 202210655492.2

14. DEVELOPMENT OF SYNTHETIC PSEUDAMINIC ACID-BASED ANTIBACTERIAL VACCINES AGAINST ACINETOBACTER BAUMANNII

  • PCT/63/260,512

13. 1,2-BENZISOSELENAZOL-3(2H)-ONE derivatives as carbapenem antibiotic adjuvants

  • United States Provisional Application Number 62/642,053 — Filed Mar 3, 2018

12. Repurposing cetylpyridinium chloride and domiphen bromide as phosphoethanolamine transferase inhibitor-based adjuvants that significantly potentiate colistin activity and resensitize mcr-1-bearing bacterial pathogens

  • United States Provisional Application 62/642,080 — Filed Mar 13, 2018

11. New cyclic peptided-based antibacterial agent

  • HKU/ref: IP00761 (PolyU ref: PAT-1139)

10. A biosensor for detection of Salmonella and its preparation and use

  • China Patent: 201711348592.6

9. A biosensor for Norovirus detection and its preparation and use

  • China Patent: 201711351548.0

8. A toxin sensor based on an organic photoelectrochemical transistor and a preparation method thereof

  • China Patent: 201711464221.4

7. A test strip for detecting broad spectrum Salmonella in food and preparation thereof

  • China Patent: 201711351523.0

6. Potent peptide-based inhibitors against BoNT/A

  • China Patent: 201510623351.2

5. Development of combinational therapy based on different serotypes of BoNT

  • China Patent: 201510306128.5

4. Methods to develop non-fluorescent labelled, tracable E. coli

  • China Patent: 201410461450.0

3. Method to develop fluorescent labelled E. coli capable of colonization in animal GI tract

  • China Patent: 201410462647.6

2. Engineering botulinum neurotoxin with elevated activity

  • US patent provisional No. 61868560
  • PCT/CN2014/084725

1. Engineering Botulinum Neurotoxin

  • US Patent Serial No. 61/169,031 (2011)
  • EU Patent Serial No. 20120039941 (2012) — Licensed by Syntaxin Ltd., Oxon, UK in 2012

Journal Papers

1. The Lancet Infectious Diseases

  • 2022 Jul; 22(7):939.
  • 2022 Feb; 22(2):167-168.
  • 2018 Jan; 18(1):37-46.
  • 2018 Jan; 18(1):24.
  • 2018 Jan; 18(1):25.
  • 2017 Mar; 17(3):256-257.
  • 2016 Mar; 16(3):291-292.

2. Signal Transduction and Targeted Therapy

  • 2023 May 30; 8(1):221.

3. The Lancet Microbe

  • 2022 Apr; 3(4):e248.
  • 2022 Nov; 3(11):e846-e856.
  • 2022 Nov 24; S2666-5247(22)00326-3.

4. Nature Microbiology

  • 2019 Dec; 4(12):2039-2043.

5. Journal of Infection

  • 2022 Aug; 85(2):174-211.
  • 2022 Oct; 85(4):436-480.

6. Drug Resistance Updates

  • 2023 Jan 11; 67:100925.

7. ACS Central Science

  • 2024 Feb 7; DOI: 10.1021/acscentsci.3c01507.
  • 2021 Sep 22; 7(9):1535-1542.

8. Journal of the American Chemical Society

  • 2021 Aug 18; 143(32):12784-12790.

9. Angewandte Chemie International Edition

  • 2020 Nov 2; 59(45):19868-19872.

10. Nature Communications

  • 2020 Sep 16; 11(1):4648.
  • 2016 Aug 3; 7:12394.

11. Eurosurveillance

  • 2023 Sep; 28(37).
  • 2019 Mar; 24(13):1800113.
  • 2017 Sep; 22(39):17-00206.

12. Emerging Microbes & Infections

  • 2024 Jan 19; 2306957.
  • 2022 Dec; 11(1):841-849.
  • 2022 Dec; 11(1):1730-1741.
  • 2022 Dec; 11(1):1049-1057.
  • 2020 Dec; 9(1):1287-1299.
  • 2020 Jan 29; 9(1):237-245.
  • 2019; 8(1):396-403.
  • 2019; 8(1):857-865.
  • 2018 Jul 9; 7(1):127.

13. International Journal of Antimicrobial Agents

  • 2023 Dec 9; 63(2):107055.
  • 2022 Jan; 59(1):106498.
  • 2018 Apr; 51(4):578-585.
  • 2022 Aug; 60(2):106628.
  • 2022 Nov-Dec; 60(5-6):106683.
  • 2022 Oct; 60(4):106645.
  • 2020 Jan; 55(1):105817.
  • 2016 Jan; 47(1):103-105.
  • 2018 Aug; 52(2):303-304.
  • 2015 Jun; 45(6):667-668.

14. eBioMedicine

  • 2024 Feb 9; 101:104998.
  • 2022 May; 79:103998.
  • 2017 May; 19:98-106.

15. Trends in Microbiology

  • 2021 Jan; 29(1):65-83.

16. Journal of Hazardous Materials

  • 2023 Jan 4; 446:130725.

17. Proceedings of the National Academy of Sciences (PNAS)

  • 2020 Mar 10; 117(10):5260-5268.

18. Gut Microbes

  • 2020 Nov 9; 12(1):1-12.

19. ACS Applied Materials & Interfaces

  • 2022 Jul 20; 14(28):31727-31736.

20. Science of the Total Environment

  • 2024 May 20; 926:171924.
  • 2024 Apr 15; 921:170903.
  • 2024 Mar 15; 916:170058.
  • 2024 Jan 1; 906:167373.
  • 2023 Dec 1; 902:166026.
  • 2023 Sep 1; 889:164302.
  • 2022 Apr 20; 818:151767.